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Dr. Michael Bertucci

Michael Bertucci, Assistant Professor of Chemistry

Assistant Professor of Chemistry

Office location: Collier 222
Office phone: 610-861-1436
Email: bertuccim@moravian.edu
Website: www.moravian.edu/bertucci-group

Education
B.S., Stevens Institute of Technology
Ph.D., University of North Carolina at Chapel Hill

Course Taught

Chem 211 Organic Chemistry I
Chem 212 Organic Chemistry II
Chem 314 Bioorganic & Medicinal Chemistry
Chem 315 Synthetic Organic Chemistry

Research Interests

My academic interests include bioorganic chemistry, synthetic organic chemistry, peptide chemistry, & chemical biology. Current research projects in our laboratory focus on the development of small molecules and peptides for the study and inhibition of bacterial quorum sensing.

Selected Publications

Schmucker, D. J., Dunbar, S. R., Shepherd, T. D., Bertucci, M.A. n→pi* Interactions in N-Acyl Homoserine Lactone (AHL) Derivatives and Their Effects on Hydrolysis Rates. J. Phys. Chem. A., 2019, 123 (13), 2537 - 2543.

Koirala, B., Hillman, R. A., Tiwold, E. K., Bertucci, M. A., Tal-Gan, Y., Defining the Hydrophobic Interactions that Drive Competence Stimulating Peptide (CSP):ComD Binding in Streptococcus pneumoniae.  Beilstein J. Org. Chem., 2018, 14, 1769 - 1777.

Hillman, R. A., Nadraws, J. W., Bertucci, M. A. The Hydrocarbon Staple & Beyond:  Recent Advanced Towards Stapled Peptide Therapeutics that Target Protein-Protein Interactions.  Curr. Top. Med. Chem., 2018, 18, 611 - 624.

Bertucci, M. A. and March, K.*, Non-Natural D-Amino Acids to Control Bacterial Virulence. Proceedings of the 24th American Peptide Symposium, 2015, 51 – 53.

Bertucci, M. A., Lee, S. J., Gagné, M. R., Selective Transamidation of 3-oxo-N-Acyl Homoserine Lactones by Hydrazine Derivatives. Org. Biomol. Chem., 2014, 12, 7197 – 7200.

Bertucci, M. A., Lee, S. J., Gagné, M. R., Thiourea-catalyzed aminolysis of N-acyl homoserine lactonesChem. Commun., 2013, 49, 2055-2057.

Recent News

Cross-Institutional Blended Learning in Medicinal Chemistry

Faculty Spotlight:  Michael Bertucci, Assistant Professor of Chemistry