- B.S. in Biomedical Science, Lynchburg College
- Ph.D. in Chemistry and Biochemistry, University of Delaware
Office phone: 610-861-1607
Office location: Collier 316
Lab location: Sally 317
I am interested in understanding how phosphorylation of Gap Junction (GJ) protein, Connexin 43 (Cx43), affects its function. GJs are pores found in plasma membranes of two neighboring cells and are made up of 12 Cx43 molecules. These pores are the only means cells have for direct cell-cell communication, allowing small molecules and ions to move from cell to cell. Cell-cell communication is key for many cellular functions, such as development, proliferation, and differentiation. Current projects are focused on using phosphomimetic mutants of Cx43 to study their ability to interact with other protein partners and to affect GJ function.